Start Your Clinical Trial Research Journey At AMR Clinical

As a trial participant, you can:

• Play an active role in your health care
• Gain access to research treatments before they are widely available
• Receive medical care from experienced physicians during the trial
• Help others by contributing to medical research
• Potentially be compensated for your time and travel

After you submit your information, an AMR Clinical Patient Experience team member will review your information and contact you to discuss clinical research enrollment opportunities.

Helpful Questions to Ask About the Clinical Trial

• What is the main purpose of the study?
• What are the chances that this drug will work?
• What kinds of risks are involved?
• How much of my time will this take?
• Does the study involve a placebo or a treatment already on the market?

Volunteers Matter

Volunteers in a clinical trial participate in the development of medical therapies that may offer better treatments and even cures for life-threatening and chronic diseases. There are both benefits and risks in participating in a clinical trial. Speak with your physician or the clinical trial center’s physicians to see if a trial is appropriate for you.

What Happens in a Clinical Trial or Study?

Here’s what typically happens in clinical trial research and what you can expect:

You continue to see your regular physician(s) for usual care throughout the study.

What Are the Different Phases of Clinical Trial Research?

Clinical trials of drugs and medical devices advance through several phases to test safety, determine effectiveness, and identify any side effects. The FDA typically requires Phase I, II, and III trials to be conducted to determine if the drug or device can be approved for further use. If researchers find the intervention to be safe and effective after the first three phases, the FDA approves it for clinical use and continues to monitor its effects.

Each phase has a different purpose:

• A Phase I trial tests an experimental drug or device on a small group of people (around 20-80) to judge its safety, including any side effects, and to test the amount (dosage).
• A Phase II trial includes more people (around 100-300) to help determine whether a drug is effective. This phase aims to obtain preliminary data on whether the drug or device works in people who have a certain disease or condition. These trials also continue to examine safety, including short-term side effects.
• A Phase III trial gathers additional information from several hundred to a few thousand people about safety and effectiveness, studying different populations and different dosages, and comparing the intervention with other drugs or treatment approaches. If the FDA agrees that the trial results support the intervention’s use for a particular health condition, it will approve the experimental drug or device.
• A Phase IV trial takes place after the FDA approves the drug or device. The treatment’s effectiveness and safety are monitored in large, diverse populations. Sometimes, side effects may not become clear until more people have used the drug or device over a longer period of time.